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What is Cystic Fibrosis?

Cystic fibrosis (CF) is a life-threatening genetic disease that primarily affects the lungs and digestive system. An estimated 30,000 children and adults in the United States (70,000 worldwide) have CF.

In people with CF, a defective gene and its protein product cause the body to produce unusually thick, sticky mucus that:

  • Clogs the lungs and leads to life-threatening lung infections.

  • Obstructs the pancreas and stops natural enzymes from helping the body break down food and absorb vital nutrients.

Quick Facts about CF.

In the United States:

  • About 1,000 new cases of CF are diagnosed each year.

  • More than 75 percent of people with CF are
    diagnosed by age 2.

  • Nearly half of the CF population is age 18 or older.